Excellent Combination of Biotech and Chemistry.
In Pursuit of the Best Quality Control.
Follow the Pace of the Progress in the Field...
Science Matters in Every Detail...
New Product Launch - EGF
We are very excited to annouce the launch of EGF. The discovery of EGF was awarded Nobel Prize in 1986. EGF is a growth factor with 53 amino acids and three intramolecular disulfide bonds (molecular weight 6046-dalton). Upon binding to EGFR on the cell surface, EGF stimulates dimerization of EGFRs, which stimulates the intrinsic protein tyrosine kisase activity of the receptor. Activated tyrosine kinase in turn initiates a signal transduction cascade and in turn exerts potent effects on cell growth, proliferation, and differentiation.
New Product Launch - SOD
Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2−) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2). SOD has powerful antinflammatory activity. SOD may reduce free radical damage to skin—for example, to reduce fibrosis following radiation for breast cancer.
A new era of oligopeptide science
With the last decades of progress in biotechnology and dermatology, oligopeptides are used as active ingredients in many cosmetic products. Effects of oligopeptides include brightening or tanning, protecting from UV exposure, preventing ageing, suppressing wrinkles, and maintaining elasticity etc. Oligopeptides are referred to as peptides containing less than 50 amino acids, which can be peptide fragment derived from known proteins or fully non-naturally occurring. Biologically active oligopeptides are being extensively studied for dermatological usage.
Traditional technology
Traditional non-amino acid therapeutics uses chemicals as active ingredients in cosmetic products. The effect depends on the feature of the chemicals used. It may have low specificity to the target thus more side effects. Modification of chemical is generally not as straightforward as peptides althought the cost of good is usually lower than peptides. Chemicals might be more penetrable to the skin but it depends on the feature of the molecule and the formulation.
Opportunities
Comparing with small molecule-based traditional therapeutics in dermatology, oligopeptides have demonstrated higher specificity and less side effects, unlimited ease of modifications, reliable dermal delivery, etc. Although the cost of goods is higher than small molecule, oligopeptides are becoming more and more popular ingredients in cosmetic products. With the progress of peptide synthesis, it is predicted that more and more oligopeptides with different biological effects will be employed in cosmetic products.
Challenges
Comparing with small molecule-based traditional therapeutics in dermatology, oligopeptides have demonstrated several advantages. The cost of peptides, however, might limit the popularity of the product and concentration of active ingredients it can be formulated in the product. Moreover, oligopeptides are larger than small-molecule chemicals thus transdermal delivery is generally more challenging. Due to instability of proteins, the half life of peptide is generally shorter than small-molecule chemical. Proper formulation of peptides in final products can aid skin penetration and elongate the half life of active ingredients.
Disclaimer
Information on this website is summarized from published literatures for education purpose only. All molecular structures listed here are for example purposes but not meant to be used as ingredients in cosmetic products.
For regulatory policy of each molecule and its use for cosmetic product, please refer to the released information of FDA or your local government. All information is provided for informational and marketing purposes only.
